Comedian Jim Gaffigan admits he lost 50 pounds using Mounjaro

Jim Gaffigan made a bold admittance astir his weight-loss journey. 

The 58-year-old confessed that his translation was little astir willpower and much astir convenience, arsenic helium credited Mounjaro (tirzepatide) for shedding 50 pounds. 

"I did appetite suppressants, truthful it's not similar I tin adjacent instrumentality immoderate pridefulness successful it," the comedian shared on "Today."

"I was brave capable to instrumentality a needle successful my stomach," helium joked.

ROSIE O'DONNELL CREDITS MOUNJARO FOR DRAMATIC WEIGHT LOSS, STUNS FANS WITH SLIMMED-DOWN APPEARANCE

Jim Gaffigan is speaking retired astir his weight-loss journey. Gaffigan is seen present successful 2015 (left) and successful 2025 (right). (Sonja Flemming/CBS via Getty Images/Frazer Harrison/Getty Images)

The injectable medicine medicine is chiefly utilized to dainty benignant 2 diabetes.

"The Skinny" comedian utilized to measurement 270 pounds, according to People. 

Despite not taking pridefulness successful his weight-loss transformation, helium pointed retired the benefits Mounjaro has had connected his body. 

"It’s large due to the fact that my knees don’t wounded lasting up," helium explained. "I’m little exhausted… It’s ever good, you know, similar the wellness benefits, like, ‘I’ll unrecorded longer,'"

Gaffigan antecedently had reservations astir the weight-loss medication. (Frazer Harrison/Getty Images)

"But I emotion it conscionable due to the fact that I consciousness better," helium said. "It is great. It’s beneficial."

Gaffigan antecedently had reservations astir the medication.

"I had precise debased expectations due to the fact that I did cognize idiosyncratic that had tried it, and they were like, ‘Oh no, I was conscionable nauseous for a week,’" helium told People astatine the time.

Actor Jim Gaffigan attends SAG-AFTRA Foundation Conversations with "American Dreamer" astatine the SAG-AFTRA Foundation Screening Room connected Sept. 19, 2019, successful Los Angeles, California.  (Vincent Sandoval/Getty Images)

"I thought my existent joyousness of eating would overpower anything," Gaffigan admitted. "That's immoderate of [the] wherefore I wanted to speech astir it, due to the fact that I astir thought it was benignant of unusual that radical were resistant to talking astir it. I don't deliberation there's thing incorrect with it."

Gaffigan isn’t the lone personage who credited Mounjaro for their slimmed-down figure.

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Rosie O’Donnell, 63, precocious took to societal media to stock a photograph of herself performing stand-up and acknowledging her overmuch smaller frame.

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"I can't judge this is maine now," she captioned the photo, which included the hashtags "#mounjaro,"#weightloss" and "#bodydismorphia."

Comedian Amy Schumer additionally praised the effects of Mounjaro successful a video clip shared connected Instagram successful March. 

In a erstwhile effort to suffer weight, the comedian said she experienced debilitating broadside effects portion utilizing Ozempic for weight-loss purposes.

Amy Schumer praised Mounjaro aft suffering from nasty broadside effects of Ozempic. (Todd Owyoung/Getty Images)

"I wanted to stock and support it 100 with you, that years ago… I tried Wegovy, and I was similar puking," said Schumer.

"I couldn't grip it…" she referred to her erstwhile weight-loss prescription.

However, things appeared to instrumentality a crook erstwhile she switched to Mounjaro.

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"My hairsbreadth is fuller, my tegument is better, I person much energy, I privation to get down much if you cognize what I mean – I'm talking astir sex."

Schumer added, "So that's been great, Mounjaro's been great… I'm having a truly bully acquisition with it and I wanted to support it existent with you astir that."

Fox News Digital's Christina Dugan Ramirez contributed to this report.