Lindsey Graham draws Democratic Senate challenger who previously lost congressional race

A South Carolina pediatrician and erstwhile Democratic House campaigner announced Wednesday that she is present moving to regenerate Republican Sen. Lindsey Graham successful the precocious enclosure of Congress. 

Dr. Annie Andrews, who mislaid by astir 14 percent points to Mace in the 2022 election, announced her run done a astir three-and-a-half-minute governmental advertisement successful which she describes Graham arsenic "full of s---." 

Andrews, wearing scrubs and seen interacting with young patients, says she has been a pediatrician successful South Carolina for astir 2 decades, and that parents spot her to "treat their kids for conscionable astir everything you tin imagine." 

She past points to a bid of X-rays. 

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Sen. Lindsey Graham, R-S.C., talks with reporters aft the legislature luncheons successful the U.S. Capitol connected Tuesday, March 11, 2025.  (Tom Williams/CQ-Roll Call, Inc via Getty Images)

"This is an X-ray of a kid with measles pneumonia, a information easy prevented by vaccines. This is simply a kid with cancer, 1 of the diseases the NIH doesn’t person the backing to survey anymore, and this is simply a kid who’s been shot, which contempt being the fig 1 origin of decease for children successful America is nary longer classified arsenic a nationalist wellness crisis," Andrews says. 

She past shows a last X-ray representation of a kid with constipation. 

"And this kid, and there’s truly nary different mode to accidental this, is rather virtually afloat of s---," Andrew says, earlier showing a video of Graham. "And this is an big who is besides wholly and unequivocally afloat of s---. Roll the tape." 

The advertisement plays respective conflicting clips of Graham successful which helium criticizes President Donald Trump, including by describing him arsenic a "kook" and telling him to "go to hell," and past videos showing Graham supporting him. 

Graham was initially captious of Trump during his 2016 statesmanlike campaign, but the legislator aboriginal became 1 of Trump’s astir vocal supporters. 

"It’s embarrassing, and South Carolina deserves better," Andrews says, announcing her run for U.S. Senate.

She past goes connected to knock respective Trump allies and Cabinet secretaries, including DOGE advisor Elon Musk, Health and Human Services Secretary Robert F. Kennedy Jr., Education Secretary Linda McMahon and Defense Secretary Pete Hegseth. 

President Donald Trump, Attorney General Pam Bondi, Health and Human Services Secretary Robert F. Kennedy Jr. and Secretary of Education Linda McMahon be a furniture gathering astatine the White House. (Reuters/Carlos Barria)

"An unelected billionaire is taking a chainsaw to Social Security, Medicare and veterans’ healthcare. The vaccine-denying encephalon worm feline is gutting our nation’s healthcare system. The wrestling woman is elbow dropping the Department of Education," Andrews says. "And a feline who can’t adjacent signifier a substance thread is moving the Department of Defense." 

"And Lindsey Graham voted to corroborate each azygous 1 of these people," Andrews claims, contempt the Senate not voting to corroborate Musk, who was a "special authorities employee." 

The advertisement cuts to Andrews banging her caput connected a table, saying, "It’s a lot." 

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"All portion backing Trump’s program to chopped taxes for millionaires and billionaires portion raising yours," she continues, showing footage of Graham speaking with Meta CEO and co-founder Mark Zuckerberg. 

Andrews says Graham, 69, has been a legislator for fractional of her beingness and "as it turns out, astir senators don’t get amended with age." 

"Lindsey is going to archer you that I’m radical, I’m brainsick due to the fact that that’s what anemic men bash erstwhile they consciousness threatened by beardown women," Andrews says. "But here’s the thing, I’m virtually a engaged ma and a pediatrician who plays peek-a-boo with my patients, watches Bluey with my kids – I emotion Bluey – and spends astir of my escaped clip shuttling them to dance, taekwondo and football." 

"Say hullo kids," Andrews says to her children successful the backmost of her vehicle. They respond, "Hi, kids!" and Andrews tells the camera, "So radical." 

"I besides conscionable hap to beryllium idiosyncratic who isn’t acrophobic of a fight," Andrew says. "And similar truthful galore of you, I’m disquieted astir what the aboriginal holds for our kids and our state."

Annie Andrews unsuccessfully ran against Rep. Nancy Mace, R-S.C., successful 2022. (Andrew Harnik/Getty Images)

"Everything from failing schools to closing hospitals. The clime situation and rising prices. To tariffs hurting our ports and car industry. Worrying won’t bash anything, but stepping up to articulation maine successful this combat conscionable might. A combat wherever we enactment communal consciousness implicit civilization wars and anticipation implicit hate. Right now, Lindsey Graham is counting connected each of america to enactment quiet. And that means 1 thing, it’s clip to get loud." 

Fox News Digital reached retired to Graham's bureau for remark connected Thursday.

In an interrogation with The Hill, Andrews reportedly said Graham "changed his presumption connected astir each issue" passim his 22 years successful the Senate and doesn’t "stand for thing different than himself." 

Graham past won re-election successful 2020, defeating Democratic challenger Jamie Harrison by 10 percent points. Harrison had raised much than $100 cardinal to unseat Graham but was unsuccessful. 

Andrews told The Hill that Harrison "ran a large campaign, but it was successful the mediate of the COVID pandemic which truly hamstrung their quality to person an effectual tract operation." She said the state present was successful a "very antithetic moment," pointing to issues that she described arsenic "attacks connected our wellness attraction system" and "attacks connected the societal information nets that are truly the bedrock and instauration of this country." 

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Andrews worked astatine the Medical University of South Carolina for astir 15 years until 2023. She told The Hill she presently has a part-time relation astatine the Children’s National Hospital successful Washington, D.C. and a module assignment astatine George Washington University. She has aesculapian licenses successful Washington, D.C., and South Carolina. She told The Hill she plans to renew her licence successful South Carolina, which is acceptable to expire adjacent month. 

If elected to the Senate, she told The Hill, she wants to prioritize making the kid taxation recognition permanent.