Arne Slot says Wataru Endo will be missing for a substantial period after he was stretchered off against Sunderland midweek, though Liverpool will need to undertake some more assessments to determine the full extent of the injury.
Joe Gomez came on for Endo at the Stadium of Light and he is back from an injury of his own. He limped off against Bournemouth last month but could start against Brighton at full-back.
Liverpool will also be without Alexander Isak, Conor Bradley, Giovanni Leoni and Jeremie Frimpong. Dominik Szoboszlai is available again after he served a one-game suspension against Sunderland.
Liverpool has lost only two of its last 18 games and is looking to secure back-to-back clean sheets for the first time since December. The second of those came against Brighton.
Midweek, Ibrahima Konate impressed with his performance against Sunderland. He has been in excellent form lately and will hope to continue that against the Seagulls.
"Impressed but not surprised," Slot said after the game against the Black Cats. "I think he's an example of almost our season. He's been so unlucky. So unlucky.
"He played sometimes 89 minutes very good and then one moment just ruined our game and his game. Not always about him, but a few times that happened and everybody was focused on his mistake.
"But footballers make mistakes and not always the ball goes in. Then just ask me about the last 10 minutes,.
" I said now the good thing is we did not concede a chance, because against City we did not concede a chance after the first minute and then it took City 84 minutes to get the second chance.
"But that one went in and so the good thing tonight was that we hardly conceded a chance at all. Ibou was a big part of that together with Virgil. But I like the whole mentality and the whole work rate of the team.
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"Ibou [Konate] played a great game against [Brian] Brobbey, who is always difficult to play against. Mo was working, doing his work off the ball a lot.
"Macca [Alexis Mac Allister] had a few very important tackles, but it was also really helpful that our fans were so loud.
"This stadium is, of course, known for the home fans, but I think the away fans tonight were incredible as well, especially in the last 20 minutes — throughout the whole game, but especially in the last 20 minutes when the team needed them."

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